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7.1 DNA Structure and replication

Understandings:
  • Nucleosomes help to supercoil the DNA
  • DNA Structure suggested a mechanism for DNA replication
  • DNA polymerases can only add nucleotides to the 3' end of a primer
  • DNA Replication is continuous on the leading strand, and discontinuous on the lagging strand
  • DNA Replication is carried out by a complex system of enzymes
  • Some regions of DNA do not code for proteins but have other important functions
Applications
  • Rosalind Franklin and Maurice Wilkin's investigation of DNA by X-Ray diffraction
  • Use of nucleotides containing dideoxyribonucleic acid to stop DNA replication in preparation of samples for base sequencing
  • Tandem repeats are used in DNA profiling
Skills
  • Utilization of molecular visualization software to analyze the association between protein and DNA with


Powerpoints
7.1_20structure_20and_20function.pdf
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Homeworks
7.1_hmwk.docx
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