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8.1 Metabolism

Understandings:
  • Metabolic pathways consist of chains and cycles of enzyme-catalyzed reactions.
  • Enzymes lower the activation energy of the chemical reactions that they catalyze.
  • Enzyme inhibitors can be competitive or non-competitive.
  • Metabolic pathways can be controlled by end-product inhibition.
Applications
  • End-product inhibition of the pathway that converts threonine is isoleucine.
  • Use of databases to identify potential new anti-malarial drugs.
Skills
  • Distinguish different types of inhibition from graphs at specified substrate concentration.
  • Calculating and plotting rates of reaction from raw experimental results.
Nature of Science
  • Developments in scientific research follow improvements in computing- developments in bioinformatics, such as the interrogation of databases have facilitated research into metabolic pathways.




Powerpoints
enzymes_8.1.pptx
File Size: 2439 kb
File Type: pptx
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enzyme_20ppt.pdf
File Size: 587 kb
File Type: pdf
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Homeworks
Enzyme Graphs for 10/14
Enzyme Homework
Links, articles and videos
Enzyme Description 10/30
Virtual Enzymes
Virtual Enzyme instruction sheet
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