Understandings:
- Metabolic pathways consist of chains and cycles of enzyme-catalyzed reactions.
- Enzymes lower the activation energy of the chemical reactions that they catalyze.
- Enzyme inhibitors can be competitive or non-competitive.
- Metabolic pathways can be controlled by end-product inhibition.
- End-product inhibition of the pathway that converts threonine is isoleucine.
- Use of databases to identify potential new anti-malarial drugs.
- Distinguish different types of inhibition from graphs at specified substrate concentration.
- Calculating and plotting rates of reaction from raw experimental results.
- Developments in scientific research follow improvements in computing- developments in bioinformatics, such as the interrogation of databases have facilitated research into metabolic pathways.
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