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Topic 11.1: Antibody Production and Vaccination

Understandings:
  • Every organism has unique molecules on the surface of its cells.
  • B lymphocytes are activated by T lymphocytes in mammals.
  • Plasma cells secrete antibodies.
  • Activated B cells multiply to form clones of plasma cells and memory cells.
  • Antibodies aid the destruction of pathogens.
  • Immunity depends upon the persistence of memory cells.
  • Vaccines contain antigens that trigger immunity but do not cause the disease.
  • Pathogens can be species-specific although others can cross species barriers.
  • White cells release histamine in response to allergens.
  • Histamines cause allergic symptoms.
  • Fusion of a tumor cell with an antibody-producing plasma cell creates a hybridoma cell.
  • Monoclonal antibodies are produced by hybridoma cells.
Applications:
  • Antigens on the surface of red blood cells stimulate antibody production in a person with a different blood group.
  • ​Smallpox was the first infectious disease of humans to have been eradicated by vaccination.Monoclonal antibodies to HCG are used to pregnancy test kits.
Skills:
  • Analysis of epidemiological data related to vaccination programs.
Nature of Science:
  • Consider ethical implications of research- Jenner tested his vaccine for smallpox in a child.
Powerpoints
11.1_antibody_production.pptx
File Size: 8908 kb
File Type: pptx
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Homeworks
11.1_hmwk.docx
File Size: 242 kb
File Type: docx
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1/29/19 Vaccine Questions and article
2018 Vocab Hmwk 
Helpful Links & Articles
Virtual Immune System Lab for 1/23/20 (Click on "Launch Interactive")
Immune system Video
​https://www.youtube.com/watch?v=kcxQyIfca4I
Test Review for 2/25/19
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